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> Has anyone had Reboxetine work for them? I think that drug has the > poorest record for efficacy among depressed patients (but seemingly > not with psychiatrists). And Desipramine is practically the same > thing as reboxetine–just with a high toxicity rate in overdose.
I hate reboxetine but maybe that’s just me. (I’m not depressed either) I’d be happy to send you some, it’s fairly cheap. M99
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Jeez! Here’s a classic example of how misinformation spreads. Let’s all be careful what we accept as fact. The following exchange from the two previous postings on this thread: << > Has anyone had Reboxetine work for them? I think that drug has the > poorest record for efficacy among depressed patients (but seemingly > not with psychiatrists). And Desipramine is practically the same > thing as reboxetine–just with a high toxicity rate in overdose.
I hate reboxetine but maybe that’s just me. (I’m not depressed either) >> I think it was I who …long ago… conjectured that reboxetine MIGHT prove to be a good med for those of us who respond well to desipramine, since both drugs retard reuptake of norepinephrine ( called noradrenaline in G.B.). As many of you know, desipramine is STILL, after many years on the market …it’s an "older tricyclic… considered to be a very effective antidepressant. It is true that an overdose of it can kill and for some people the side-effects (overheating, constipation, sun hypersensitivity, suicidal tendencies, etc) make it a poor candidate for a doctor to prescribe, but it does NOT have a poor track record in alleviating depression. On the contrary, it has one of the best, which is why it’s still used. Living in the United States, I have NO experience using reboxetine, but I wanted to try it. But obviously if despramine is "practically the same thing" as reboxetine, as the previous poster stated, it is either a good antidepressant or the poster knows not whereof he speaks… Isn’t this obvious logic, everyone?
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In rereading my last post, I apologize for the rant. The bottom line is this: As we all know, different ADs work totally differently for different people. It seems that PERHAPS different ones of us have different causes, chemically speaking, for our own particular depression. Some people here, like myself, have had satisfactory relief from depression ONLY with desipramine, but would gladly change to another newer med if it had less of its side-effects and worked as well. I’d be interested to know how THIS SPECIFIC sub-group responds to reboxetine…. even tho’ the question is moot as we will never get it here in the US since companies here seem to be more interested in having new patents on their own propriatary chemicals.
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> In rereading my last post, I apologize for the rant. The bottom line is this: > As we all know, different ADs work totally differently for different people. It > seems that PERHAPS different ones of us have different causes, chemically > speaking, for our own particular depression. > Some people here, like myself, have had satisfactory relief from depression > ONLY with desipramine, but would gladly change to another newer med if it had > less of its side-effects and worked as well. I’d be interested to know how THIS > SPECIFIC sub-group responds to reboxetine…. even tho’ the question is moot as > we will never get it here in the US since companies here seem to be more > interested in having new patents on their own propriatary chemicals.
Desipramine and rebox are similiar in that they both increase norepinephrine. I take a small dose of desipmramie to combat sedation from remeron. It really helps alot, and i get a nice tingly feeling throughout my body. But if i increase dosage, my anxiety and heart rate increase. I would suspect if someone is suffering from depression and anxiety, i would not suggest an SNRI (desipr and rebox) unless used in combo with a sedation medication. geno
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Reboxetine is precribed in the US now? I remember a few years ago when i ordered some overseas. I haven’t really tried in a while, but i remember getting a good buzz from it, and it did make me feel better in the short term. I believe from what i’ve read its a selective, clean med. On another note i’ve ordered Tianeptine overseas, to try again, in trial with the vit/supp I take. Its just so expensive (aren’t they all) $60 for 60 pills. I wish the FDA would get it approved for prescription. Damn the man, I mean the currupt big brother. -Just an average Joe.
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Has anyone had Reboxetine work for them? I think that drug has the poorest record for efficacy among depressed patients (but seemingly not with psychiatrists). And Desipramine is practically the same thing as reboxetine–just with a high toxicity rate in overdose.
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Ya, I gave it a try. It’s a solid antidepressant. I tried it to augment my Luvox to try to deal with residual depressive symptoms (most notably lack of energy). Instead what I experienced was slightly greater resilience to stress and improvement in my comorbid attention-deficit (non-hyperactive) symptoms. However, reboxetine did not help me at all with my major problem of low energy. So I stopped it to make room (as it were) to try augmenting with something else. Sodah
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